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Interestingly, we also show that kynurenine, a metabolite derived from tryptophan following inflammatory activation of IDO1 [46,47,48], is elevated in TTR-V30M patients but not in age-matched healthy controls

Although there was a significant decrease in CT scores pre and postintervention in both groups, the decrease in the HABIT group was significantly greater than that of the control group [37.5% (28.6%, 50%) vs

IL-10, IL-13, and IL-15) may have anabolic effects and modify the contractile function of the skeletal muscle

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